Eric J Small Selected Research

Ketoconazole (Nizoral)

12/2014	Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens.
10/2013	The effect of prior androgen synthesis inhibition on outcomes of subsequent therapy with docetaxel in patients with metastatic castrate-resistant prostate cancer: results from a retrospective analysis of a randomized phase 3 clinical trial (CALGB 90401) (Alliance).
3/2010	Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy.
12/2007	Phase II study of ketoconazole plus granulocyte-macrophage colony-stimulating factor for prostate cancer: effect of extent of disease on outcome.
4/2007	Adrenal androgen levels as predictors of outcome in prostate cancer patients treated with ketoconazole plus antiandrogen withdrawal: results from a cancer and leukemia group B study.
6/2006	Activities and accomplishments of the cancer and leukemia group B genitourinary committee.
3/2004	Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583).
8/2002	Low dose ketoconazole with replacement doses of hydrocortisone in patients with progressive androgen independent prostate cancer.

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Eric J Small Research Topics

Disease

234	Prostatic Neoplasms (Prostate Cancer) 04/2022 - 02/2002
106	Neoplasms (Cancer) 04/2022 - 06/2002
42	Neoplasm Metastasis (Metastasis) 02/2022 - 08/2002
31	Disease Progression 12/2018 - 08/2002
24	Leukemia 10/2020 - 08/2002
20	Renal Cell Carcinoma (Grawitz Tumor) 01/2022 - 04/2004
12	Carcinoma (Carcinomatosis) 01/2021 - 12/2003
11	Adenocarcinoma 12/2021 - 08/2002
9	Pain (Aches) 11/2014 - 12/2003
8	Fatigue 01/2022 - 03/2005
6	Neutropenia 01/2022 - 12/2003
5	Exanthema (Rash) 01/2021 - 03/2007
5	Hypertension (High Blood Pressure) 01/2021 - 11/2008
4	Melanoma (Melanoma, Malignant) 12/2020 - 04/2013
3	Proteinuria 01/2021 - 11/2008
3	Urinary Bladder Neoplasms (Bladder Cancer) 01/2019 - 07/2005
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2016 - 09/2002
3	Margins of Excision 05/2008 - 08/2002
3	Transitional Cell Carcinoma 10/2005 - 04/2003
2	Febrile Neutropenia 01/2022 - 03/2005
2	Carcinogenesis 07/2019 - 01/2018
2	Hypoxia (Hypoxemia) 07/2019 - 04/2004
2	Circulating Neoplastic Cells 12/2017 - 09/2017
2	Diarrhea 01/2017 - 09/2012
2	Cancer Pain 10/2015 - 01/2013

Drug/Important Bio-Agent (IBA)

79	AndrogensIBA 02/2022 - 02/2002
54	Prostate-Specific Antigen (Semenogelase)IBA 02/2022 - 06/2002
54	Hormones (Hormone)IBA 01/2020 - 06/2002
30	Docetaxel (Taxotere)FDA Link 01/2022 - 12/2003
22	Prednisone (Sone)FDA LinkGeneric 01/2022 - 10/2004
21	sipuleucel-T (APC8015)FDA Link 01/2021 - 06/2005
19	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 07/2003
19	AntigensIBA 12/2020 - 02/2002
18	Abiraterone AcetateIBA 01/2019 - 03/2010
17	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2002
14	Bevacizumab (Avastin)FDA Link 01/2022 - 04/2004
12	apalutamideIBA 02/2022 - 01/2018
12	enzalutamideIBA 01/2022 - 05/2015
11	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 11/2016 - 01/2003
10	Biological ProductsIBA 01/2019 - 01/2003
10	Estramustine FDA Link 02/2011 - 12/2003
9	Testosterone (Sustanon)FDA Link 08/2021 - 08/2002
9	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2012 - 04/2004
8	Ketoconazole (Nizoral)FDA LinkGeneric 12/2014 - 08/2002
7	abirateroneIBA 01/2022 - 01/2013
7	Pharmaceutical PreparationsIBA 09/2021 - 06/2004
7	Gemcitabine FDA Link 01/2021 - 04/2003
7	Tyrosine Kinase InhibitorsIBA 07/2019 - 09/2002
7	prostatic acid phosphataseIBA 08/2015 - 10/2003
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2003
6	IpilimumabIBA 01/2021 - 03/2007
6	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 04/2003
6	cabozantinibIBA 11/2019 - 02/2013
6	gallium 68 PSMA-11IBA 06/2019 - 01/2017
6	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2017 - 10/2004
5	Phenobarbital (Luminal)FDA Link 11/2021 - 01/2019
5	RNA (Ribonucleic Acid)IBA 12/2020 - 08/2017
5	taxaneIBA 01/2020 - 01/2006
5	Interferon-alpha (Interferon Alfa)IBA 01/2014 - 04/2004
5	ixabepilone (BMS 247550)FDA Link 06/2011 - 03/2005
5	ErbB Receptors (EGF Receptor)IBA 09/2009 - 09/2002
5	Gefitinib (Iressa)FDA Link 01/2008 - 09/2002
4	Immune Checkpoint InhibitorsIBA 01/2021 - 10/2012
4	Sunitinib (Sutent)FDA Link 11/2019 - 01/2017
4	Hemoglobins (Hemoglobin)IBA 10/2019 - 04/2013
4	AntibodiesIBA 01/2018 - 05/2006
4	Monoclonal AntibodiesIBA 04/2013 - 07/2004
4	Insulin-Like PeptidesIBA 07/2012 - 03/2007
4	Suramin (Suramin Sodium)IBA 06/2006 - 08/2002
4	Carboplatin (JM8)FDA LinkGeneric 10/2005 - 04/2003
4	herbal preparation PC-SPESIBA 09/2005 - 02/2002
4	Diphosphonates (Bisphosphonates)IBA 12/2003 - 05/2002
3	DNA (Deoxyribonucleic Acid)IBA 11/2021 - 07/2019
3	Alkaline PhosphataseIBA 10/2019 - 12/2003
3	Cell-Free Nucleic AcidsIBA 01/2017 - 05/2015
3	VaccinesIBA 09/2015 - 07/2006
3	Estrogens (Estrogen)FDA Link 10/2009 - 05/2002
3	Cancer VaccinesIBA 05/2007 - 10/2003
3	Androgen Antagonists (Antiandrogens)IBA 04/2007 - 07/2003
3	thiamine triphosphorate (TTP)IBA 07/2006 - 07/2004
2	Circulating Tumor DNAIBA 01/2020 - 12/2017
2	PlatinumIBA 01/2020 - 10/2005
2	LigandsIBA 12/2019 - 03/2005
2	Phosphotransferases (Kinase)IBA 12/2019 - 07/2019
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 07/2019 - 10/2007
2	bicalutamide (Casodex)FDA LinkGeneric 05/2019 - 01/2019
2	RadiopharmaceuticalsIBA 01/2019 - 12/2013
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2018 - 01/2017
2	Dehydroepiandrosterone (DHEA)IBA 12/2017 - 10/2009
2	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2017 - 02/2013
2	Opiate AlkaloidsIBA 10/2015 - 01/2013
2	sargramostim (Leukine)FDA Link 09/2015 - 06/2006

Therapy/Procedure

123	Therapeutics 04/2022 - 02/2002
114	Castration 02/2022 - 08/2002
46	Drug Therapy (Chemotherapy) 01/2021 - 09/2004
33	Immunotherapy 01/2021 - 06/2003
15	Prostatectomy (Retropubic Prostatectomy) 08/2021 - 06/2002
14	Radiotherapy 01/2021 - 06/2002
8	Aftercare (After-Treatment) 11/2021 - 11/2004
2	Life Support Care 10/2015 - 11/2014